Endocrine Abstracts

Introduction: Thyroid autoimmunity and diabetes mellitus type 2 (DM2) are the commonest endocrine disorders in the general population. The aim of the study was to investigate whether there is an association between thyroid autoimmunity and β-cell secretion in patients with impaired fasting glucose (IFG) and/or impaired glucose tolerance (IGT).Methods/design: 501 patients (381 females) 46.5±14.2 years with IFG and/or IGT and autoimmune thyroidit...

Background: Arterial stiffness is a well-established surrogate marker of vascular properties and arterial dysfunction in patients with type 2 diabetes mellitus (DM2). We aimed to investigate whether optimization of DM2 therapy with, additional to metformin, novel antiglycemic agents may improve arterial wall properties and achieve better glycemic control.Methods: We enrolled 99 consecutive patients (male gender=63.3%) receiving metformin for DM2 who did ...

Background: Patients with type 2 diabetes (T2D) are at higher risk for thrombotic events and as a result cardiovascular disease. Platelet function may be used to assess prothrombotic state in patients with cardiovascular disease.Purpose: We aimed to investigate whether the administration of novel antidiabetic agents influence platelet function in TDM2 patients.Patients and Methods: We 60 enrolled consecutive patients with T2DM, on ...

Introduction: Patients with type 2 diabetes mellitus (T2DM) exert a higher risk for thrombotic events. Platelet reactivity may be used to assess prothrombotic state in such patients. The aim of this study was to investigate whether the administration of novel antidiabetic agents could influence the platelet reactivity in T2DM patients.Patients and methods: We enrolled 99 consecutive patients (males=63.3%), 64.92±8.3 years old, receiving metformin fo...